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Dipartimento di Fisica - Politecnico di Milano

[16/01/2020 - 11:30]

Dr. Renzo Vanna (CNR-IFN)

"The challenge of facing unmet clinical needs with Raman-based approaches: some examples"

 

gio 16/01/2020 - 11:30 - Aula Rossa, Dipartimento di Fisica

 

ABSTRACT
The potentialities and advantages of Raman spectroscopy (RS) have significantly come to light in the last three decades. This has been enabled by the improvement of laser sources, by the introduction of new optical configurations/enhancement strategies and by the growing overlap between biophysical and biomedical physicists. Thanks to my recent experience of introducing and optimizing Raman-based approaches in hospitals, I will show some examples of studies started by clear questions arisen from the interaction with medical doctors. In details, I will describe the use of spontaneous Raman imaging of bone marrow cells for the classification of leukaemia subtypes, the use of Raman imaging for the characterization and assessment of breast microcalcification, and the use of RS or Surface Enhanced RS for the study of biofluids or circulating DNA. A specific focus will be given on the technological needs and limitations that nowadays still prevent the introduction of RS in clinics.

"Biomedical applications of Raman spectroscopy and confocal Raman spectral imaging"

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